Mohamed Issa

Mohamed Issa

EVP, Head of U.S., Incyte | Leading with purpose, building with clarity, delivering impact for patients

Incyte•New York City Metropolitan Area, United States

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Experience20+ Years

Executive Overview

I’ve seen firsthand how access to healthcare can be shaped by circumstance rather than need. That perspective has guided my career at the intersection of science, business, and service—focused on scaling innovation so it reaches the patients who need it most.Today, I serve as Executive Vice President at Incyte, where I lead the U.S. enterprise across all functions, overseeing a multibillion-dollar portfolio spanning Hematology, Oncology, and Immunology. My focus is on aligning strategy, execution, and culture to deliver sustained growth, strong commercial performance, and durable organizational capability.My team’s remit is clear: translate breakthrough science into consistent, real-world impact at scale.I believe the differentiator for enduring companies is the ability to build high-performing, purpose-driven organizations—anchored in clarity, high standards, accountability, and trust. When those elements are in place, teams execute with discipline, adapt with speed, and extend the reach of innovation.If you are a leader, partner, or builder who wants to create meaningful impact, scale innovation, and help more patients benefit from scientific progress, I would welcome the opportunity to connect.

Career Timeline

Professional employment history
  • IncyteCurrent
    2025–Present· 1 yr 9 mos
    • Executive Vice President, Head of US Commercial Current
      Apr 2026–Present
    • Executive Vice President, Head of U.S Oncology
      2025–Apr 2026
  • 2025–Present· 1 yr 9 mos
    • Board MemberCurrent
      2025–Present
  • Jun 2012–2025· 12 yrs 7 mos
    • SVP, US Commercial, Immunology - Dermatology and Rheumatology
      Sep 2022–2025
    • Vice President, U.S Commercial, Neuroscience
      2021–Sep 2022
    • Head, U.S Oncology Franchise Strategy
      Apr 2019–2021
    • U.S General Manager, Sports Medicine
      Sep 2017–Apr 2019
    • Regional Business Director - Neuroscience
      Jun 2015–Sep 2017
    • Regional Business Director - Hepatology and Immunology
      Feb 2014–Jun 2015
    • Product Director, Hepatology Marketing
      Jun 2012–Feb 2014
  • May 2011–Feb 2014· 2 yrs 9 mos
    • CEO & Co-Founder (Acquired)
      May 2011–Feb 2014
  • Jul 2009–Jun 2012· 2 yrs 11 mos
    • Director, Strategy and Business Development
      Jun 2011–Jun 2012
    • Senior Brand Manager, Marketing: Worldwide pharmaceutical operations/ Neuroscience and CNS
      Jul 2009–Jun 2011
  • Jun 2006–Jul 2009· 3 yrs 1 mo
    • Hepatology Sales
      Aug 2008–Jul 2009
    • Brand Manager, Hepatology Marketing
      Jun 2006–Aug 2008

Education

Doctor of Pharmacy - PharmD

St. John's University

MBA

Economics and Finance

New York University - Leonard N. Stern School of Business

Executive Relationship Map

Reports To
Mohamed Issa
Vice Chair & President
Chief Financial Officer
Chief Technology Officer
Chief Operating Officer

Executive Network Preview

BizKonnect has mapped this leadership network including reporting hierarchies, peer connections, and cross-functional relationships.

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Skills & Expertise

20 of 20 skills
CommercializationKOL developmentPharmacyPharmacologyGastroenterologyProduct LaunchPharmaceutical business developmentManaged CarePharmaceutical commercial operationsInfectious DiseasesRheumatologyStrategyCross-functional Team LeadershipNeuroscienceClinical TrialsHepatitis CHospital SalesPharmaceutical SalesPharmaceutical IndustryCardiology