Besufekad Alemayehu

Besufekad Alemayehu

CDIO | SVP, Digital & Technology | Industrial AI in Manufacturing & Supply Chain | Business Transformation Office | Biopharma

Merck•Cambridge, Massachusetts, United States

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Experience21+ Years
LevelCXO

Executive Overview

SVP-level digital and technology executive in global biopharma manufacturing and supply chain, delivering measurable value from transformation at scale in regulated operations (GxP). I currently serve as Senior Vice President and Chief Digital/Technology leader at Merck & Co., Inc., accountable for a ~$1B-class technology and capital portfolio, and I also lead the Business Transformation Office—aligning strategy, governance, and execution across operations, quality, engineering, and supply chain. A central focus of my work is industrializing AI in manufacturing and supply chain—moving from pilots to production to drive step-change performance (planning and scheduling, inventory and service, predictive reliability, faster root-cause investigation, yield/throughput optimization, and end-to-end visibility), while strengthening compliance, cybersecurity, and data foundations. I’m known for translating complex technology into business outcomes, building and scaling high-performing global teams, and executing with disciplined operating rhythms—modernizing platforms (ERP/MES/data), advancing automation and digital operations, and delivering transformation with clear KPIs and value realization. Recognition includes being named the 2025 Manufacturing Leader of the Year by the Manufacturing Leadership Council, Boston ORBIE CIO of the Year, and a finalist for CIO of the Year at the National ORBIE Awards. I enjoy connecting with leaders advancing digital transformation, AI, and operational excellence across regulated manufacturing and supply chain.

Career Timeline

Professional employment history
  • MerckCurrent
    Sep 2021–Present· 5 yrs 1 mo
    • Senior Vice President and Chief Digital Transformation Officer, Global MMD DigitalCurrent
      Sep 2022–Present
    • Vice President & CIO, Global MMD
      Sep 2021–Sep 2022
  • Oct 2015–Sep 2021· 5 yrs 11 mos
    • VP, Pharmaceutical Operations & Technology IT
      Oct 2015–Sep 2021
  • 2010–Oct 2015· 5 yrs 9 mos
    • VP IT, Global Solutions Center for Industrial Development, Execution, & Automation Systems (IDEAS)
      2014–Oct 2015
    • Vice President, IT - Global Manufacturing, Quality & Corporate Operations
      Apr 2011–Oct 2015
    • Director, Automation Engineering, Manufacturing Systems & IT
      Feb 2010–Dec 2014
    • Director, Manufacturing Execution Systems (MES) & IT
      2010–Dec 2014
  • 2005–Mar 2010· 5 yrs 2 mos
    • Director, IT & Automation Engineering
      2005–Mar 2010

Education

BA

Pontifical University of St. Thomas Aquinas - Angelicum

Master of Science (M.Sc)

Leadership - (IT)

Northeastern University

Executive Relationship Map

Reports To
Besufekad Alemayehu
Vice Chair & President
Chief Financial Officer
Chief Technology Officer
Chief Operating Officer

Executive Network Preview

BizKonnect has mapped this leadership network including reporting hierarchies, peer connections, and cross-functional relationships.

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Skills & Expertise

20 of 20 skills
AnalyticsRegulatory AffairsEngineeringBusiness ProcessLeadershipRegulatory SubmissionsManufacturing EngineeringBiotechnology Industry21 CFR Part 11Laboratory Information Management System (LIMS)Quality SystemGood Laboratory Practice (GLP)GMPFDAMedical DevicesCross-functional Team LeadershipDrug DevelopmentManufacturing Process ImprovementProcess AutomationBiotechnology