Alnylam Pharmaceuticals

Biotechnology ResearchCambridge, Massachusetts, United States
Est. 2002Public Company2,625 Employees
Employees
~2,625
Founded
2002

About Alnylam Pharmaceuticals

Alright, here is the paraphrased text: SILENCE DISEASE. AMPLIFY LIFE.™ Alnylam is a prominent independent biopharmaceutical company and the trailblazer in RNA interference (RNAi) therapeutics, an innovative method for treating diseases by “silencing” the genes responsible for causing or contributing to them. Established in 2002 by a team of distinguished researchers and biotech pioneers, Alnylam's efforts across more than two decades have produced the essential breakthroughs and advancements that enabled the field of RNAi therapeutics to exist. In 2018, our first commercial product, and the world's inaugural RNAi therapeutic, received approval. From that point, four additional Alnylam-developed medicines have gained approval, and we are actively engaged in developing new treatments for both rare and common conditions. We are a global, diverse organization of over 2,500 employees. We take pride in cultivating a fun, inclusive, and dynamic workplace that enables staff to reach their full potential. This is why we are regularly recognized as a top employer by The Boston Globe (2015-24), Science Magazine (2018-24), Fast Company (Best Workplaces for Innovators 2020-25), and LinkedIn (2024). Our headquarters are located in Cambridge, Massachusetts (U.S.), with additional offices across North America, Europe, Asia, and South America. Refer to our social media community guidelines: https://bit.ly/2FcRhJy. Important: If you need to report an adverse event or product complaint, reach out to medinfo@alnylam.com, or call us at the following numbers: for North America, 877.ALNYLAM (877.256.9526); for Europe, +31 20 369 7861.

Key Facts
Approximately 2,625 employees globally
Headquartered in Cambridge, Massachusetts, United States
Operates in Biotechnology Research
Founded in 2002

Executive Leadership Team

Dr. Yvonne Greenstreet
Dr. Yvonne Greenstreet
Chief Executive Officer
Since 2022
Jeff Poulton
Jeff Poulton
Group Chief Financial Officer
Since 2019
Kevin Fitzgerald
Kevin Fitzgerald
Chief Scientific Officer
Since 2018
Mike Tirozzi
Mike Tirozzi
Senior Vice President, Chief Information and Data Officer
Since 2024
Piyush Sharma
Piyush Sharma
Chief Ethics and Compliance Officer
Since 2022
Pushkal Garg
Pushkal Garg
Chief Research and Development Officer
Since 2025

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Alnylam Pharmaceuticals Executive Leadership Team

Dr. Yvonne Greenstreet
Dr. Yvonne Greenstreet
Chief Executive Officer
Since 2022
Jeff Poulton
Jeff Poulton
Group Chief Financial Officer
Since 2019
Kevin Fitzgerald
Kevin Fitzgerald
Chief Scientific Officer
Promoted from Director, Senior Director, Vice President, SVP, CSO. Currently leading an innovative and diverse Research Department of >100. Responsible for all aspects of novel drug development including chemistry, screening, lead identification, technology platform, preclinical, clinical POC, portfolio development and culture. Multiple successful business and drug development alliances. Key Achievements: •Led cross-functional teams to discover, refine, and advance two liver-based siRNA delivery systems from invention to clinic. •Inventor/co-inventor on over 50 patents including three novel FDA approved RNAi therapeutic products, and a large pipeline of potential therapeutics undergoing clinical trials •Played key role in forming ~$2 billion in transformative alliance deals (Genzyme/Sanofi and Regeneron) •Lead teams that delivered 4 CTA filings in 24 months by identifying, vetting, and executing on pipeline goals targeting four different genetically validated diseases. All four compounds rapidly achieved positive Phase 1 results and 3/4 are now approved while the other continues in development. Several were awarded FDA breakthrough and/or Orphan Drug status.
Since 2018
Mike Tirozzi
Mike Tirozzi
Senior Vice President, Chief Information and Data Officer
Since 2024
Piyush Sharma
Piyush Sharma
Chief Ethics and Compliance Officer
Member of Executive Leadership Team reporting into the Chief Executive Officer. Lead Alnylam's Ethics & Compliance organization, and manage all aspects of the Company's global compliance program. Drive strategic priorities and a solutions-oriented approach on our mission to build a best-in-class compliance program. Establish compliance governance across the enterprise, and present regularly to Alnylam's Board of Directors.
Since 2022
Pushkal Garg
Pushkal Garg
Chief Research and Development Officer
Since 2025

Business Focus Areas

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Business Focus Areas
PharmaceuticalsbiotechBiopharmaDrug DevelopmentRNAiRare diseases
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Alnylam Pharmaceuticals Org Chart & Organizational Structure

Alnylam Pharmaceuticals, a biopharmaceutical company, is led by Dr. Yvonne Greenstreet, who serves as Chief Executive Officer. The company's executive leadership team includes several key officers overseeing major functions. In the Information Technology function, Mike Tirozzi holds the position of Senior Vice President and Chief Information and Data Officer, under whom the Enterprise Architecture sub-function is led by Vasant Jadhav, the Chief Technology Officer. The Research & Development function is overseen by Pushkal Garg as Chief Research and Development Officer and Kevin Fitzgerald as Chief Scientific Officer. In the Finance function, Jeff Poulton serves as Group Chief Financial Officer. Piyush Sharma holds the dual role of Chief Ethics and Compliance Officer within the Compliance function and is also associated with the Ethics and Integrity function. Tolga Tanguler serves as Executive Vice President and Chief Commercial Officer, holding responsibility for both the Marketing and Sales functions.